论文部分内容阅读
传统上认为帕金森病(IPD)是黑质和黑质纹状体通路的变性,造成运动系统障碍的一种疾病。但近年的研究表明IPD的病变范围非常广泛,所以临床上IPD患者往往伴有情绪、认知、感觉和ANS障碍等方面的改变,有时上述病变甚至成为主要的临床表现。其中ANS功能障碍患病率高,约90％,IPD患者或多或少有ANS功能障碍表现,如皮脂溢、便秘、性功能障碍、流涎、尿失禁、吞咽困难、多汗、直立性低血压等,在受治疗的患者中表现更为明显。这可能是因为与未受
Parkinson’s disease (IPD) is traditionally considered to be a degeneration of the substantia nigra and nigrostriatal pathways, a disorder that causes disorders in the motor system. However, recent studies have shown that the range of IPD lesions is very wide, so clinical IPD patients are often associated with emotional, cognitive, sensory and ANS disorders and other changes, and sometimes the above lesions even become the main clinical manifestations. Among them, the prevalence of ANS dysfunction is about 90%. Patients with IPD have more or less the manifestation of ANS dysfunction such as seborrhea, constipation, sexual dysfunction, salivation, urinary incontinence, dysphagia, hyperhidrosis, orthostatic hypotension And so on, the performance of patients treated more obvious. This may be because of and not affected