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目的:了解部分地区献血员丙型肝炎病毒(HCV)的感染状况及流行因素。方法:对山东省某地区以自然村为单位整群抽取435例有偿献血员进行调查,用酶联免疫吸附方法(ELISA)对其血清进行抗-HCV检测。结果:献血员HCV感染率为21.15％(92/435),HCV感染率在有献血浆史者为44.22％,高于无献血浆史者(9.38％),1995年前献血者(33.83％)高于1996年后献血者(9.84％),献血频率每3个月多于1次者(24.65％)高于每3个月少于1次者(15.67％);Logistic多因素分析显示:献血浆史和1995年(含)前献血是HCV感染的主要危险因素。结论:有偿献血员HCV感染率较高,献血浆史和1995年前献血是HCV感染的主要影响因素。
Objective: To understand the infection status and epidemic factors of hepatitis C virus (HCV) in blood donors in some areas. Methods: A total of 435 compensated blood donors were collected from villages in a village of Shandong Province. Anti-HCV was detected by enzyme-linked immunosorbent assay (ELISA). Results: The prevalence of HCV in blood donors was 21.15% (92/435). The prevalence of HCV infection was 44.22% in those with plasma donations, higher than those without blood donation (9.38%), before blood donation in 1995 (33.83%), (9.86%) after 1996. The frequency of blood donation was more than once every three months (24.65%) and less than once every three months (15.67%). Logistic multivariate analysis showed that blood donation The history of plasma and blood donation before (and) in 1995 were the major risk factors for HCV infection. Conclusion: The HCV infection rate of paid blood donors is high. The history of blood donation and blood donation before 1995 are the main influencing factors of HCV infection.