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新生儿一过性甲状腺机能减退症是一种暂时性病理状态,经一个时期后即可恢复正常,表现为促甲状腺激素(TSH)增高和甲状腺激素(T_4)降低。根据日本全国调查发生率为1/60000-70000,相当于克汀病的1/5—1/6。欧洲发生率较高(1/8000)。男女之比为1:1(克汀病为1:2),但欧美以男孩多见。 本病病因有以下几方面:1.抗甲状腺制剂。巴塞多氏病等甲状腺机能亢进症的妊妇,服用的抗甲状腺药物(他巴唑、丙硫氧嘧啶)可通过胎盘到胎儿,抑制胎儿甲状腺合成甲状腺激素,致新生儿发
Hypothyroidism Hypothyroidism is a transient pathological condition that returns to normal after a period of time characterized by an increase in thyrotropin (TSH) and a decrease in thyroid hormone (T_4). According to the Japanese national survey, the prevalence rate is 1/600 to 70000, which is equivalent to 1/5 to 1/6 of cretinism. A higher incidence in Europe (1/8000). Male to female ratio of 1: 1 (cretinism is 1: 2), but more common in Europe and America to boys. The etiology of the disease in the following areas: 1. Antithyroid preparations. Barton’s disease and other hyperthyroidism in pregnant women, taking anti-thyroid drugs (methimazole, propylthiouracil) through the placenta to the fetus, inhibition of fetal thyroid synthesis of thyroid hormone, resulting in neonatal hair