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目的 评价临床各种诊断幽门螺杆菌 ( HP)感染的方法、手段的可靠性与参照性。方法 对 2 0 0例具有消化道症状的患儿进行 1 3 C尿素呼气试验 ,并与胃镜下胃粘膜改变、胃粘膜尿素酶试验、组织学检查及 Giem sa染色、血 HP- Ig G相对照。结果 经统计学处理 ,1 3 C尿素呼气试验与胃粘膜快速尿素酶试验、组织学检查均无显著性差异 ,与特异性抗体检测有显著性差异 ,与胃镜下胃粘膜病变的检出有非常显著性差异。结论 1 3 C尿素呼气试验在诊断小儿 HP感染中具有安全性及可靠性。胃粘膜快速尿素酶试验、组织学检查与 1 3 C尿素呼气试验具有可比性
Objective To evaluate the reliability and reference of various clinical methods and means of diagnosing Helicobacter pylori (HP) infection. Methods A total of 200 children with gastrointestinal symptoms were enrolled in the 13 C urea breath test. Gastroscopy and gastric mucosal changes, gastric mucosal urease test, histological examination and Giem sa staining, blood HP-Ig G phase Control. The results of statistical analysis, 13 C urea breath test and gastric mucosa rapid urease test, histological examination showed no significant difference with the specific antibody test significant differences, and gastroscopic gastric mucosal lesions were detected Very significant difference. Conclusion 1 3 C urea breath test in the diagnosis of children with HP infection is safe and reliable. Gastric mucosal rapid urease test, histological examination and 13 C urea breath test comparable