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选择我院2011年11月—2012年8月收治的职业性急性1,2-二氯乙烷(1,2-DCE)中毒病例38例,采用顶空气相色谱-质谱法对其中12例进行血中毒物检测。结果显示,12例患者中有7例患者在发病6～18 h送血标本检出1,2-DCE成分,其中3例同时检出丙酮成分;5例发病24～72 h送血检测,均未检出1,2-DCE成分,仅检出丙酮成分,其中1例检出二氯甲烷、甲苯,1例检出二硫化碳。提示急性1,2-DCE中毒患者应早期进行血毒物检测,1,2-DCE阳性对明确病因及临床诊断有重要价值。
38 cases of occupational acute 1,2-dichloroethane (1,2-DCE) poisoning admitted to our hospital from November 2011 to August 2012 were selected and 12 of them were studied by headspace gas chromatography-mass spectrometry Blood poisoning test. Results showed that in 12 of 12 patients, 1,2-DCE was detected in blood samples from 6 to 18 h after onset, of which 3 samples were also detected for acetone content. Blood samples were obtained from 5 to 24 h No detectable 1,2-DCE components were detected only for acetone components, of which 1 case detected methylene chloride and toluene, and 1 case detected carbon disulfide. Suggest that patients with acute 1,2-DCE poisoning should be early detection of blood poisoning, 1,2-DCE positive for a clear cause and clinical diagnosis of great value.