【摘 要】
：
Four new octadecanoid derivatives (1-4) including a pair of enantiomers (1/2),along with 12 known analogues (5-16),were isolated from the seeds oflpomoea nil.Their structures were determined by detailed spectroscopic analyses and comparison with reported
【机 构】
：
School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China;School of Bio
论文部分内容阅读
Four new octadecanoid derivatives (1-4) including a pair of enantiomers (1/2),along with 12 known analogues (5-16),were isolated from the seeds oflpomoea nil.Their structures were determined by detailed spectroscopic analyses and comparison with reported data of structurally related compounds,with the absolute configurations of 1 and 2 being assigned by an in situ dimolybdenum ECD method.Our bioassays revealed that these isolates did not show ABTS radical scavenging activity while 10 and 13 displayed better α-glucosidase inhibitory activity than the positive control acarbose (IC50 167.7 ± 1.55 μmol·L-1),with IC50 of 92.73 ± 3.12 and 11.39 ± 2.18 μmol·L-1,respectively.
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