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2型糖尿病每日胰岛素用药>60d的102例患者,加用格列美脲,观察治疗前后。结果:治疗后空腹血糖,餐后2小时血糖,糖化血红蛋白较治疗前有所下降有统计学意义(P<0.01),胰岛素的用量及低血糖发生减少有统计学意义(P<0.01),体重较前下降有统计学意义(<0.05)。结论:格列美脲联合胰岛素方案可有效降低血糖,同时可显著降低胰岛素用量,降低低血糖的发生及体重增加等不良反应,依从性好。
Type 2 diabetes daily insulin medication> 60d of 102 patients, plus glimepiride, observed before and after treatment. Results: The fasting blood glucose, postprandial 2-hour postprandial blood glucose and HbA1c decreased compared with those before treatment (P <0.01), the amount of insulin and the decrease of hypoglycemia were statistically significant (P <0.01) Compared with the previous statistics (<0.05). Conclusion: glimepiride combined with insulin regimen can effectively reduce blood glucose, while significantly reducing the amount of insulin, reducing the incidence of hypoglycemia and weight gain and other adverse reactions, good compliance.