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目的分析喜炎平联合丙种球蛋白治疗小儿重症手足口病的临床应用效果。方法 60例行重症手足口病治疗的患儿,随机分为对照组和研究组,各30例。对照组给予一般常规性治疗,研究组给予喜炎平联合丙种球蛋白治疗,对两组患者的治疗效果及手术指征进行分析和对比。结果经治疗,两组患儿的住院时间、神经受累时间、口腔炎愈合时间、退烧时间、疱疹消退时间对比差异具有统计学意义(P<0.05)。对照组的总有效率为87.5%,研究组的总有效率为96.7%,组间比较差异有统计学意义(P<0.05)。结论对重症手足口病患儿采用喜炎平联合丙种球蛋白治疗,效果显著,值得在临床医学上推广使用。
Objective To analyze the clinical effect of Xiyanping combined with gamma globulin in the treatment of severe hand-foot-mouth disease in children. Methods Sixty children with severe HFMD were randomly divided into control group and study group, with 30 cases in each group. The control group was given conventional treatment. The study group was given Xiyanping combined with gamma globulin treatment. The therapeutic effect and surgical indications of the two groups were analyzed and compared. Results After treatment, there were significant differences in hospitalization time, nerve involvement time, healing time of stomatitis, fever time and herpes regression time between two groups (P <0.05). The total effective rate of the control group was 87.5%, the total effective rate of the study group was 96.7%, the difference between the two groups was statistically significant (P <0.05). Conclusion The treatment of severe hand-foot-mouth disease patients with Xiyanping combined with gamma globulin, the effect is significant, it is worth to promote the use of clinical medicine.