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目的探讨甲胎蛋白异质体(AFP-L3)与肝癌的关系。方法选择160例临床检测甲胎蛋白(AFP)为阳性的肝病患者,分别检测血清中AFP和AFP-L3,分析甲胎蛋白异质体在肝癌诊断中的意义。结果血清中甲胎蛋白异质体的含量与肝癌有明显的相关性,两者的关联度有统计学意义。结论甲胎蛋白异质体检测在肝癌的诊断中有一定的临床意义。
Objective To investigate the relationship between AFP-L3 and liver cancer. Methods 160 patients with AFP positive liver disease were selected. AFP and AFP-L3 were detected in serum. The significance of alpha-fetoprotein heterogeneity in the diagnosis of hepatocellular carcinoma was analyzed. Results The level of alpha-fetoprotein in serum was significantly correlated with liver cancer, and the correlation between them was statistically significant. Conclusion The detection of alpha-fetoprotein heteroplasmy has a certain clinical significance in the diagnosis of liver cancer.