Iron, Dopamine, and α-Synuclein Interactions in at-Risk Dopaminergic Neurons in Parkinson's Dis

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Parkinson\'s disease (PD) is recognized as the second most common neurodegenerative disorder after Alzheimer disease.Although a fascinating 200-year journey of research has revealed the multifaceted nature of PD [1,2],its fundamental features are the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and depletion of dopamine (DA) in the striatum.
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