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胃肠道,特别是小肠及阑尾,含有丰富的淋巴组织,是一个重要的免疫器官,胃肠炎性疾病与免疫机制密切相关而又极为复杂。这方面研究很多但均未明确。致病因子作为致敏原可通过胃肠道局部免疫反应,引起局部炎症及全身性病变。而炎性病变产物又可作为新的抗原,促使炎症加重或复燃,进而形成慢性顽固性病变。本专题牵涉范围很广,本文仅就慢性胃炎及炎症性肠病作一些介绍。慢性胃炎的免疫学改变本病极为常见,据近年国内胃镜资料,占受检人
The gastrointestinal tract, especially the small intestine and appendix, is rich in lymphoid tissue and is an important immune organ. Gastrointestinal inflammatory diseases are closely related to the immune mechanism and are extremely complicated. Many studies in this area but not clear. Pathogenic factors as allergens through the gastrointestinal tract local immune response, causing local inflammation and systemic disease. The inflammatory lesions and products can be used as a new antigen, promote inflammation or rekindle, and then the formation of chronic intractable disease. This topic involves a wide range, this article only on chronic gastritis and inflammatory bowel disease make some introduction. Immunological changes in chronic gastritis The disease is extremely common, according to the domestic gastroscopy data, accounting for subjects