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为研究婴儿巨细胞病毒(CMV)肝炎的临床特点及免疫功能变化,将39例婴儿CMV肝炎病人分为先天感染组及围生期感染组,对二组主要临床表现及实验室检查结果进行比较;并对39例患儿不同临床期的细胞免疫功能进行检测。结果:先天感染组的症状较围生期组重,总胆红素、结合胆红素、PT及γ-GT均较围生期组高,病死率及先天畸形发生率亦明显高于围生期组;CMV肝炎患儿细胞免疫功能受损。结论:应重视孕期的CMV感染监测,以降低CMV感染的发病率,提高人口素质。
In order to study the clinical features and immune function of CMV hepatitis, 39 cases of infantile CMV hepatitis were divided into congenital infection group and perinatal infection group. The main clinical manifestations and laboratory test results of two groups were compared ; And 39 cases of children with different clinical cell immune function tests. Results: Compared with perinatal group, the symptoms of congenital infection were heavier than those in perinatal group. Total bilirubin, conjugated bilirubin, PT and γ-GT were higher than those in perinatal group, and mortality and congenital malformation were also significantly higher than those in perinatal Group; CMV hepatitis children with impaired cellular immunity. Conclusion: CMV infection monitoring during pregnancy should be emphasized to reduce the incidence of CMV infection and improve population quality.