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目的了解慢性脑供血不足患者接受氟桂利嗪胶囊联合脑心通胶囊治疗的临床效果及安全性。方法纳入本院2013年-2015年收治确诊为慢性脑供血不足患者为本次研究对象,随机抽取70例并根据其接受治疗方案差异将其分为对照组(给予氟桂利嗪胶囊治疗)与观察组(联合脑心通胶囊治疗),每组各有患者35例。对比2组患者药物临床应用效果及不良反应。结果评估2组患者临床疗效,观察组患者治疗总有效率显著优于对照组,差异有统计学意义(P<0.05);记录2组患者血液流变学相关指标及脑血流等改善情况,观察组均明显优于对照组,差异有统计学意义(P<0.05);2组患者均无发生严重不良反应,差异无统计学意义(P>0.05)。结论慢性脑供血不足患者应用氟桂利嗪胶囊联合脑血通胶囊方案治疗,疗效相对更为显著,更好改善患者相关临床指标,无不良反应降低患者治疗依从性,有安全高效的优点,值得临床推广。
Objective To investigate the clinical effects and safety of flunarizine capsule and Naoxintong capsule in patients with chronic cerebral insufficiency. Methods Totally 70 patients with chronic cerebral insufficiency admitted to our hospital from 2013 to 2015 were selected and randomly divided into control group (Flunarizine capsule treatment) and control group Observation group (combined Naoxintong capsule treatment), each group of 35 patients with each. Comparison of two groups of patients with clinical effects and adverse drug reactions. Results The clinical efficacy of the two groups of patients was evaluated. The total effective rate of the observation group was significantly better than that of the control group (P <0.05). The improvement of hemorheology indexes and cerebral blood flow were recorded in the two groups. The observation group were significantly better than the control group, the difference was statistically significant (P <0.05); 2 groups of patients had no serious adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion Patients with chronic cerebral insufficiency should be treated with Flunarizine Capsule combined with Naoxuetong Capsule. The curative effect is relatively more significant, and the clinical indexes of patients with chronic cerebral insufficiency are better than those without Naoxintong Capsules. There is no adverse reaction to reduce the patients’ compliance with treatment, which is safe and effective. Clinical promotion.