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目的分析一起耐甲氧西林金黄色葡萄球菌医院感染的危险因素,探索有效的控制措施。方法查看病房环境、回归性病例分析,利用PFGE方法对耐甲氧西林金黄色葡萄球菌(MRSA)菌株进行同源性分析。结果2007年6～7月MRSA感染9例,罹患率为15%;病房分布有聚集性;9份菌株药敏结果基本相同;5份菌株具有高度同源性;主要的危险因素有抗菌素的频繁使用、大面积的烧伤、与感染者同房、换床、陪护和探视等。结论合理使用抗生素,尽量减少侵袭性操作、严格隔离MRSA感染者、严格控制人员尤其探视人员进入、加强医护人员的手部卫生、加强器械及环境消毒、及时采样送检是预防和控制MRSA感染的关键。
Objective To analyze the risk factors of methicillin-resistant Staphylococcus aureus nosocomial infection and explore effective control measures. Methods Ward environment and retrospective case analysis were used to analyze the homology of methicillin-resistant Staphylococcus aureus (MRSA) strains by PFGE method. Results Nine cases were infected with MRSA from June to July in 2007, with an attack rate of 15%. Ward distribution was aggregated. Nine strains had the same drug susceptibility results. Five strains had high homology. The main risk factors were frequent antibiotics Use, extensive burns, sharing with infected persons, changing beds, escorting and visiting. Conclusion Reasonable use of antibiotics to minimize invasive operations, strict isolation of MRSA infections, strict control of personnel, especially access to personnel to strengthen the hand hygiene of medical staff to strengthen the disinfection of equipment and the environment, timely sampling and inspection is to prevent and control MRSA infection The essential.