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自从1913年Gallavardin等对收缩中期喀喇音,收缩晚期杂音的认识以来,已有半个多世纪的发展。1963年Barlow证明心尖区收缩晚期杂音提示二尖瓣返流,常伴非喷射性喀喇音。此音起源于腱索,因收缩期二尖瓣脱垂到左房所致。他将此临床听诊、心电图改变,心血管造影显示的二尖瓣脱垂,统称为“二尖瓣脱垂综合征”(简称MVP)。1966年Criley以电影心血管造影研究方法,首先证明上翻的二尖瓣后叶脱垂高峰与收缩
More than half a century has passed since Gallaardin et al. In 1913, who were aware of the contractions of the mid-tones of the Harmony and the contraction of advanced murmurs, In 1963, Barlow proved that the contraction of the apex of the apical area murmur prompted mitral regurgitation murmur, often accompanied by non-injection of Castillo. This tone originated in the tendons, due to systolic mitral valve prolapse to the left atrium. He will this auscultation, ECG changes, cardiovascular angiography showed mitral valve prolapse, collectively referred to as “mitral valve prolapse syndrome” (referred to as MVP). In 1966 Criley to film cardiovascular angiography research methods, first to prove the flip up of mitral valve prolapse prolapse and contraction