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据报道,慢性炎症性肠病可伴发胰腺炎;多数作者认为这是由治疗炎症性肠病所用的药物、克隆病侵犯十二指肠或硬化性胆管炎所致。本文报告6例患者均无可致胰腺疾病的其他因素。病人和方法;病人选自1983年至1987年芬兰Oulu大学中心医院的513例炎症性肠病。计6例(男4例,女2例,年龄23～52岁)因上腹部疼痛伴尿淀粉酶或血淀粉酶明显升高拟诊胰腺炎入院。均作详细的实验室,胰腺分泌功能(胰泌素试验)、结肠镜、胃镜和逆行胰胆管造影(ERCP)检查。内镜检查时从结肠四个不同区域至少取出3块活组织,胃和十二指肠也各取活检。若ERCP失败时作静脉胆道造影。按Kasugai等标准将胰腺造影分为正常(O)、轻度(Ⅰ)和中度(Ⅱ)胰腺炎。
It is reported that chronic inflammatory bowel disease can be associated with pancreatitis; most authors believe this is due to the treatment of inflammatory bowel disease drugs, Crohn’s disease violations of duodenum or sclerosing cholangitis. This report reports no other patients with pancreatic disease in 6 patients. Patients and Methods; The patients were selected from 513 cases of inflammatory bowel disease at Oulu University Central Hospital, Finland from 1983 to 1987. Six cases (4 males and 2 females, aged from 23 to 52 years old) were enrolled for pancreatitis due to the obvious increase of upper abdominal pain with urinary amylase or amylase. Detailed labs, pancreatic secretion (secretin test), colonoscopy, endoscopy and ERCP were performed. Endoscopic examination of four different areas from the colon removed at least three living tissues, stomach and duodenum were also taken biopsy. If ERCP fails intravenous cholangiography. According to Kasugai and other criteria will be divided into normal pancreatic (O), mild (Ⅰ) and moderate (Ⅱ) pancreatitis.