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目的:研究自拟平甲抑亢方加减联合丙基硫氧嘧啶治疗甲状腺功能亢进症患者的临床疗效。方法:将130例甲状腺功能亢进症患者随机分为观察组与对照组各65例,观察组患者采用自拟平甲抑亢方加减联合丙基硫氧嘧啶治疗,对照组仅采用丙基硫氧嘧啶治疗,观察比较两组患者治疗前后血清甲状腺素水平、中医学症状及基本体征改善情况。结果:两组患者治疗后血清T3、T4水平明显下降,血清TSH水平明显上升,与治疗前比较差异具有统计学意义(P<0.05)。观察组患者显效28例,有效33例,无效4例,总有效率为93.85%;对照组患者显效13例,有效36例,无效16例,总有效率为75.38%,组间临床疗效比较差异具有统计学意义(P>0.05)。结论:采用平甲抑亢方加减联合丙基硫氧嘧啶治疗甲亢临床疗效更显著,值得临床推广使用。
Objective: To study the clinical efficacy of self-made Ping Jia Yi Kang side plus combined with propylthiouracil in patients with hyperthyroidism. Methods: 130 cases of hyperthyroidism were randomly divided into observation group and control group, 65 cases in each group. Patients in observation group were treated with self-made Ping Jia Yi Kang side plus propylthiouracil and control group only with propylthiourea Oxypyrimidine treatment were observed and compared between the two groups before and after treatment, serum thyroxine levels, symptoms and symptoms of patients with basic signs of improvement. Results: After treatment, the levels of serum T3 and T4 were significantly decreased and the level of serum TSH was significantly increased in both groups. The difference was statistically significant compared with that before treatment (P <0.05). In the observation group, 28 cases were markedly effective, 33 cases were effective, 4 cases were ineffective, and the total effective rate was 93.85%. In the control group, 13 cases were markedly effective, 36 cases were effective, 16 cases were ineffective and the total effective rate was 75.38% Statistically significant (P> 0.05). Conclusion: The treatment of Hyperthyroidism with Ping Jia Yi Kang side addition and subtraction combined with propylthiouracil clinical efficacy is more significant, worthy of clinical promotion and use.