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目的：探讨各型病毒性肝炎红细胞体积分布宽度（ＲＤＷ）的变化及临床意义；方法：仪器选用美国Ｃｏｕｌｔｅｒ－ＪＴ型全血细胞计数仪；结果：ＲＤＷ在急性肝炎组为１３．８±２．８，慢性轻型肝炎组为１４．２±３．０，慢性中型肝炎组为１７．０±５．７，慢性重型肝炎组为２４．８±３．４，肝硬化组为２０．３±３．６，分别与对照组１３．９±２．７相比，除急性肝炎组、慢性轻型肝炎组Ｐ＞０．０５外，其它各组Ｐ值均＜０．０１，ＲＤＷ与血清白蛋白呈显著负相关关系（ｒ＝－０．９６６）。重型肝炎存活病例ＲＤＷ平均值为１９．２±３．４。重型肝炎死亡病例ＲＤＷ平均值为２４．８±４．６，两组相比较Ｐ＜０．０１。结论：病毒性肝炎患者ＲＤＷ的改变可以反映肝病病情及肝功能损害的严重程度。
Objective: To investigate the changes and clinical significance of the volume distribution width (RDW) of various types of viral hepatitis. Methods: The American Coulter-JT whole blood cytometer was used. Results: The RDW in the acute hepatitis group was 13.8 ± 2.8 , 14.2 ± 3.0 in chronic mild hepatitis group, 17.0 ± 5.7 in chronic moderate hepatitis group, 24.8 ± 3.4 in chronic severe hepatitis group and 20.3 ± 3 in cirrhosis group. 6, respectively, compared with the control group 13.9 ± 2.7, except acute hepatitis group, chronic mild hepatitis group P> 0.05, the other groups P values were <0.01, RDW and serum albumin was significant Negative correlation (r = -0.966). The average RDW of patients with severe hepatitis was 19.2 ± 3.4. The average RDW of death from severe hepatitis was 24.8 ± 4.6, P <0.01 compared with the two groups. Conclusion: The changes of RDW in patients with viral hepatitis can reflect the severity of liver disease and the severity of liver dysfunction.