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目的观察不同动物实验感染广州管圆线虫情况,为进一步研究云南省广州管圆线虫病提供实验依据。方法从褐云玛瑙螺中分离广州管圆线虫第Ⅲ期幼虫,人工感染SD大鼠、昆明小鼠、豚鼠和家兔,观察感染情况。结果小鼠未能感染广州管圆线虫;豚鼠、家兔在感染广州管圆线虫后未获得成虫,仅发现少量幼虫寄生;感染不同时间后可在大鼠脊髓、脑、心和肺等部位发现各期广州管圆线虫。结论动物实验证明小鼠、豚鼠和家兔不是广州管圆线虫的适宜终末宿主,大鼠可作为广州管圆线虫感染理想的实验动物。
Objective To observe the infection of Trichinella spiralis in different animal experiments and provide experimental evidence for further study on Trichinella spiralis in Guangzhou, Methods The third instar larvae of A. cantonensis were isolated from A. niloticus and infected with SD rats, Kunming mice, guinea pigs and rabbits. The infection was observed. Results The mice were not infected with A. cantonensis. Guinea pigs and rabbits did not get adults after infection with A. cantonensis, only a few larvae were found to be parasitic. After being infected for different times, they could be found in the spinal cord, brain, heart and lung All stages of Guangzhou round worm. Conclusion Animal experiments show that mice, guinea pigs and rabbits are not suitable terminal hosts of A. cantonensis. Rats can be used as ideal laboratory animals for infection of C. elegans.