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IgA肾病是以肾小球系膜区存在着IgA或IgA为主的免疫沉积物为特征的一类肾小球疾病。其典型的临床表现为反复发作性肉眼或镜下血尿和(或)蛋白尿,发病前(2～3天)或同时常有呼吸道感染或肠道感染,其感染源可能为病毒或细菌。一般无浮肿,初次发病时高血压约占10%,高血压的出现与预后有关。血清中IgA常升高。本病的确诊主要依赖肾活检,特别是免疫病理检查。其发病率与临床表现存在着一定的地区差异。我国尚无确切的统计,但从国内一些报道来看它在肾活检资料中约占19～32%。早期报
IgA nephropathy is a type of glomerular disease characterized by IgA or IgA-dominated immune deposits in the glomerular mesangial area. The typical clinical manifestations of repeated episodes of macroscopic or microscopic hematuria and / or proteinuria, before the onset of (2 to 3 days) or at the same time often respiratory or intestinal infections, the source of infection may be viruses or bacteria. Generally no edema, the initial incidence of hypertension about 10%, the emergence of hypertension and prognosis. IgA in serum is often elevated. The diagnosis of the disease mainly depends on renal biopsy, especially immunopathological examination. The incidence and clinical manifestations of the existence of certain regional differences. China has no exact statistics, but according to some domestic reports, it accounts for about 19 to 32% of the total number of cases of renal biopsy. Early newspaper