论文部分内容阅读
目的观察卡维地洛联合内镜套扎术对食管静脉曲张再次出血的防治效果。方法选择2013年10月—2014年11月来河南能源焦作煤业集团中央医院治疗食管静脉曲张破裂出血的患者106例,随机将患者分成对照组和治疗组,每组各53例。对照组采用普萘洛尔+内镜套扎术共同治疗,治疗组采用卡维地洛+内镜套扎术共同治疗,观察两组患者治疗效果及安全性。结果治疗组药剂使用量、出血率、病死率与对照组相比,差异均有统计学意义(P<0.05);两组患者不良反应发生率相比,差异无统计学意义(P>0.05)。结论对食管静脉曲张再次出血的患者采用卡维地洛联合内镜套扎术治疗效果明显,能有效的降低药剂使用量,减少出血率及病死率,安全性高,可推广应用。
Objective To observe the effect of carvedilol combined with endoscopic ligation on the prevention and treatment of esophageal variceal bleeding again. Methods From October 2013 to November 2014, 106 cases of esophageal variceal bleeding were treated in Central Hospital of Henan Energy Jiaozuo Coalition Group. The patients were randomly divided into control group and treatment group, with 53 cases in each group. The control group was treated with propranolol + endoscopic ligation, and the treatment group was treated with carvedilol + endoscopic ligation. The therapeutic effect and safety of the two groups were observed. Results Compared with the control group, the dosage, bleeding rate and mortality of the treatment group were significantly different (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05) . Conclusion The re-bleeding of esophageal varices in patients with carvedilol combined with endoscopic ligation effect is obvious, can effectively reduce the dose, reduce bleeding and mortality, high safety, and can be extended.