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重症肌无力是神经肌肉间兴奋传递障碍所引起的一种慢性疾病。具有缓解与复发的倾向,其特征是横纹肌特别容易疲乏无力,即肌肉运动后很快发生疲劳,经休息或用抗胆硷酯酶类药物后症状迅速减轻或消失。本病主要累及与眼球运动、颜面表情、咀嚼、吞咽、说话等有关的肌肉,有时颈肌、躯干、四肢等肌肉也可受累,严重病例,呼吸肌也发生障碍。
Myasthenia gravis is a chronic disease caused by disorders of neuromuscular transmission. With the tendency of relieving and recurrence, the feature is that striated muscle is particularly vulnerable to fatigue, that is, fatigue occurs soon after muscle movement, and the symptoms are quickly lightened or disappeared after resting or using anticholinesterase drugs. The disease mainly involves the eye movement, facial expression, chewing, swallowing, talking and other related muscles, and sometimes muscle, trunk, limbs and other muscles can also be involved, severe cases, respiratory muscle disorders.