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14例糖尿病非感染性慢性腹泻患者用二种不同的治疗方法进行自身对照。即在同一患者的二次腹泻时分别应用针灸治疗或各种药物治疗,分别观察二种疗法达止泻所需天数。发现针灸止泻所需天数(平均5.3天)显著少于药物止泻所需天数(平均11.4天),P<0.001。并测定其中7例患者针灸前后血清β-内啡肽样物质(β-Ep)浓度。发现针灸前所有患者的β-Ep浓度(平均38.7pg/ml)均低于正常对照组(88.3±21.3pg/ml),而针灸止泻后显著升高(平均393.2pg/ml),P<0.001,提示针灸对该类患者的止泻作用有一定近期疗效,β-Ep很可能在针灸止泻机理中起一定作用。
Fourteen patients with non-infectious chronic diarrhea with diabetes underwent self-control with two different treatments. That is, in the same patient with secondary diarrhea, respectively, acupuncture or various drug treatment, respectively, two kinds of therapy were observed for the number of days to stop diarrhea. The number of days required for acupuncture to stop diarrhea (5.3 days on average) was found to be significantly less than the number of days required for drug antidiarrheal (mean, 11.4 days), P <0.001. Serum β-endorphin-like substance (β-Ep) was measured before and after acupuncture in 7 patients. The results showed that the concentration of β-Ep in all patients before acupuncture was 38.7pg / ml on average (88.3 ± 21.3pg / ml), while acupuncture was significantly increased after stopping diarrhea (393.2pg / ml on average), P < 0.001, suggesting that acupuncture for these patients have some immediate effect of anti-diarrhea, β-Ep may play a role in the mechanism of acupuncture diarrhea.