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作者用小鼠进行曼氏血吸虫获得性免疫力的研究。结果证明对攻击感染免疫力的差异是与不同管尾蚴的变异有关,而不是宿主免疫反应的变异。本研究用的曼氏血吸虫系波多黎各品系。小鼠为远系繁殖的 TO、TF_1和近亲繁殖的 A、AKR、BALR/C、CBA/Ca、C_(57) BL 等7个品系。实验表明这7个品系小鼠经初次感染20～30条尾蚴所激发的抗再感染免疫水平的差异很大。免疫水平的差异在同一次实验中较在不同次实验之间要小得多,其主要原因是由于不同次的实验用不同管的尾蚴而造成的免疫力变异。
The authors used mice for Schistosoma mansoni acquired immunity research. The results demonstrate that the difference in immunity to challenge infection is related to variation in different C. cercariae, rather than variation in the host’s immune response. The Schistosoma mansoni used in this study is a Puerto Rico strain. The mice were outbred TO, TF_1 and inbred strains A, AKR, BALR / C, CBA / Ca, C 57 (57) BL. Experiments show that the seven strains of mice infected by the initial infection of 20 to 30 cercariae challenge anti-re-infection immunity vary widely. The difference in immunity levels was much smaller in the same experiment than in different experiments, mainly due to the variation in immunity due to different tube cercariae in different experiments.