论文部分内容阅读
为了评价前S系统——前-S(1)抗原/前-S(2)抗体在乙型肝炎的诊断和预后中的价值,作者应用酶免疫法测定了69例HBsAg阳性的HBV感染者血清中的上述两项指标及有关指标。这69例HBV感染者包括急性乙型肝炎14例,慢性肝病30例(慢性迁延性肝炎6例、慢性活动性肝炎14例、肝硬变10例)和无症状携带者25例。在此研究之前6个月内这些患者的抗-HBe曾为阳性。结果:在所有慢性肝病和HBsAg阳性的无症状携带者中,均检测到前-S(1)抗原,但这些患者中前-S(2)抗体均为阴性,而急性乙型肝炎组中有12例(85.7％)前-s(2)抗体为阳性。
To evaluate the value of the pre-S (1) antigen / pre-S (2) antibody in the diagnosis and prognosis of hepatitis B, the authors used enzyme immunoassay to determine the serum levels of 69 patients with HBsAg-positive HBV infection In the above two indicators and related indicators. The 69 cases of HBV infection included 14 cases of acute hepatitis B, 30 cases of chronic liver disease (chronic persistent hepatitis in 6 cases, chronic active hepatitis in 14 cases, cirrhosis in 10 cases) and asymptomatic carriers in 25 cases. Anti-HBe was positive in these patients within the 6 months prior to this study. Results: Pre-S (1) antigens were detected in all asymptomatic carriers of chronic liver disease and HBsAg positive, but the pre-S (2) antibodies were negative in these patients, whereas in the acute hepatitis B group 12 (85.7%) pre-s (2) antibodies were positive.