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目的探讨IgGA(B)抗体与新生儿溶血病的关系。方法对2693例新生儿黄疸症状的患儿作ABO、Rh(D)血型检查,直接抗人球蛋白试验、游离抗体测定及放散试验。结果在2693例患儿中母婴ABO血型不合所致新生儿溶血病有334例,母婴O/A所致的HDN为161例,O/B所致的HDN为171例,A/ABHDN1例,B/ABHDN1例。结论对新生儿黄疸患儿及时进行ABOHDN血型血清学检测,有助于早期诊断及时诊治。
Objective To investigate the relationship between IgGA (B) antibody and hemolytic disease of newborn. Methods A total of 2693 neonates with jaundice were tested for ABO, Rh (D) blood type, direct anti-human globulin test, free antibody test and discharge test. Results There were 334 cases of neonatal hemolytic disease in 2693 cases of neonatal hemolytic disease due to incommunicable ABO blood group, 161 cases of HDN caused by mother-infant O / A, 171 cases of HDN caused by O / B and 1 case of A / ABHDN , B / ABHDN1 cases. Conclusion The timely detection of ABOHDN serology in neonates with jaundice may be helpful for early diagnosis and treatment.