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目的:观察补阳还五合剂在家免Ⅲ型超敏反应制模后及制模中给药对体内RBC-C3bR,SIL-2R,CIC的影响。方法:采用皮下注射正常马血清,建立Ⅲ型超敏反应模型,分别于制模后及边制模边给药,间断取血测定RBC-C3bR,SIL-2R,CIC的变化。结果:实验组用药后RBC-C3bR,CIC,SIL-2R均降低(P<0.01)。结论:补阳还五合剂对Ⅲ型超敏反应的形成有抑制作用。
OBJECTIVE: To observe the effect of Buyang Huanwu Mixture on the RBC-C3bR, SIL-2R, and CIC after injecting into model III hypersensitivity home-prepared and injection molding. METHODS: Subcutaneous injection of normal horse serum was used to establish a type III hypersensitivity model, which was administered after molding and side molding respectively. Blood was taken intermittently to determine the changes of RBC-C3bR, SIL-2R and CIC. Results: RBC-C3bR, CIC, and SIL-2R were all decreased in the experimental group (P<0.01). Conclusion: Buyang Huanwu Mixture can inhibit the formation of type III hypersensitivity reaction.