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目的探讨肝叶切除术在肝门部胆管癌治疗中的作用。方法回顾性分析了1991年1月~1995年12月间收治的52例肝门部胆管癌的临床资料。结果52例中手术切除17例,切除率327%,手术死亡率为59%。切除组中14例兼行不同范围的肝叶切除,其中8例为治愈性切除,治愈性切除组与姑息性切除组平均生存期为211个月和75个月(P<0.05)。切除组与引流组疗效有显著性差异(P<0.05)。结论联合肝叶切除术可提高肝门部胆管癌的治愈性切除率,改善术后病人的预后。
Objective To explore the role of hepatectomy in the treatment of hilar cholangiocarcinoma. Methods The clinical data of 52 cases of hilar cholangiocarcinoma admitted from January 1991 to December 1995 were retrospectively analyzed. Results Among the 52 cases, 17 cases underwent surgical resection. The resection rate was 32.7% and the surgical mortality rate was 5.9%. In the resection group, 14 patients underwent hepatic lobectomy with different ranges, 8 of whom were curative resections. The mean survival time of the curative resection group and the palliative resection group was 211 month and 75 months (P<0. 05). There was a significant difference in curative effect between the resection group and the drainage group (P<0.05). Conclusion Combined liver lobectomy can improve the curative resection rate of hilar cholangiocarcinoma and improve the prognosis of postoperative patients.