某高校大学新生乙型肝炎病毒感染状况及防治策略

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目的了解高校大学生乙型肝炎病毒(HBV)感染现状,在当前学校入学新生体检取消乙型肝炎(乙肝)检测时,为学校制定乙肝预防保健措施提供科学依据。方法对徐州市某高校2007~2009级入学新生乙肝血清学检测结果进行分析。结果 2007~2009级入学新生共体检11 871人,HBsAg阳性405人,阳性率为3.41%,其中男生HBsAg阳性率为4.70%,女生HBsAg阳性率为2.64%,农村新生HBsAg阳性率为4.35%,城市新生HBsAg阳性率为2.41%。HBsAg阳性率男生高于女生、农村高于城市,其差异均有统计学意义,并且存在南方高于北方等地区性差异。HBV感染模式以“大三阳”和“小三阳”为主,构成比例分别为42.47%和36.54%。结论徐州市某高校新生存在乙肝感染的潜在危险,要采取综合性的防治措施减少和控制乙肝的传播。 Objective To understand the current status of hepatitis B virus (HBV) infection among college students and to provide a scientific basis for the development of hepatitis B prevention and care measures in schools when abolishing hepatitis B (HBV) test at the current school entrance examination. Methods The serological test results of hepatitis B in freshmen from 2007 to 2009 in a university in Xuzhou City were analyzed. Results A total of 11 871 students were enrolled from 2007-2009, with 405 positive for HBsAg. The positive rate was 3.41%. The positive rate of HBsAg in boys was 4.70%, the positive rate of HBsAg in girls was 2.64%, the positive rate of HBsAg in rural students was 4.35% The positive rate of HBsAg in city freshmen was 2.41%. The positive rate of HBsAg in boys was higher than that in girls and in rural areas was higher than that in urban areas. The difference was statistically significant, and there were regional differences such as the south being higher than the north. The pattern of HBV infection was mainly “Sanyangyang” and “Sanyangyang”, with the proportions of 42.47% and 36.54% respectively. Conclusion There is a potential risk of hepatitis B infection among freshmen in a university in Xuzhou. Comprehensive prevention and control measures should be taken to reduce and control the spread of hepatitis B.
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