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两个月前,Sousa 医师在本刊提出过由输血所引起的与输入过量铁相关的某种免疫抑制机制。下面,笔者报告可证实上述见解的一个病例。1980年元月,到我院就诊的一名45岁男性病人,主诉虚弱,视物模糊,心动过速。我们凭临床和化验室所见作出了顽固性贫血的诊断。骨髓检查见细胞成分轻度减少,伴巨幼红细胞分化以及效应性红细胞生成之完全缺失。血小板和白细胞尚属相对地正常。给病人进行对症治疗,每3—4星期给予含有4个单位的红细胞浓缩物。皮下注射去铁
Two months ago, Sousa presented in this issue some immunosuppressive mechanism associated with transfused iron that is associated with an excess of iron. Below, I report a case that confirms the above findings. In January 1980, a 45-year-old male patient attending our hospital complained of weakness, blurred vision and tachycardia. We have clinically and laboratory findings made of a diagnosis of intractable anemia. Bone marrow examination showed a slight decrease in cellular components, with megaloblastic differentiation and complete loss of effector erythropoiesis. Platelets and white blood cells are still relatively normal. The patient is treated symptomatically with 4 units of erythrocyte concentrate every 3-4 weeks. Subcutaneous injection to the iron