论文部分内容阅读
在60年代末期发现利福平(RMP),同时对氨苯砜的耐药性日渐增加,是怀疑用传统的单一氨苯砜治疗麻风病价值的根本原因。当证明利福平对麻风菌有强力杀菌作用时,在1970—1980这10年间,它便成为治疗麻风病必不可少的药物组份。此后逐渐了解到麻风类似结核,是一个有大量菌群的分枝杆菌疾病,可用类似于结核病的联合药物治
The discovery of Rifampicin (RMP) in the late 1960s, coupled with an increasing resistance to dapsone, is the underlying cause of suspicion of the value of conventional monotherapy for the treatment of leprosy. When proving that rifampicin has a strong bactericidal effect on leprosy, it became an indispensable pharmaceutical ingredient for the treatment of leprosy over the 10 years 1970-1980. Since then, Leprosy-like tuberculosis has been gradually recognized as a mycobacterium disease with a large number of bacterial flora that can be treated with a combination of drugs similar to tuberculosis