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作者报道1例45岁女性阿狄森氏病病人,用类固醇按常规剂量方法治疗过程中出现色素沉着、垂体蝶鞍扩大并同时有垂体功能紊乱,出现泌乳、促性腺激素及生长激素分泌减少等现象。提示可能发生分泌ACTH 的垂体肿瘤。当作者调整类固醇激素的使用方法,不必用超生理剂量的类固醇,即每天早晚各给服氢化考的松5mg,每日早晨给氟考的松0.1mg 及晚上8时30分给地塞米松0.25mg,即可控制 ACTH
The authors report a 45-year-old female Addison’s disease patients with steroid treatment by conventional dosage method appears pigmentation, pituitary sella enlargement and pituitary dysfunction, there is a decrease in lactation, gonadotropin and growth hormone secretion phenomenon. Tip may occur secretion of ACTH pituitary tumors. When the author adjusts the use of steroid hormones, do not have to use a super-physiological dose of steroid, that is, each morning and evening to give hydrocortisone 5mg, daily morning to flucarbazone 0.1mg and 8:30 to dexamethasone 0.25 mg, you can control ACTH