论文部分内容阅读
目的对乙型肝炎后肝硬化反复发作的影响因素进行分析。方法选择45例治疗后反复发作肝硬化的乙型肝炎患者作为观察组,另选取同期首次发病乙型肝炎肝硬化患者45例作为对照组,对两组患者免疫组化检查结果及肝组织病理学检查等因素进行定量分析。结果慢性乙型肝炎(CHB)病史、手术史、肝脏组织炎症程度高、父母阴性肝炎史、饮酒史、胆固醇低、白细胞低、胆碱酯酶低、胃底静脉曲张、肝脏组织免疫组化HBcAg表达、高PCR-HBVDNA定量等是导致乙型肝炎后肝硬化反复发作的重要影响因素。结论影响乙型肝炎后肝硬化反复发作因素多样,熟悉掌握危险因素并给予抗病毒治疗等是预防肝硬化反复发作的重要手段。
Objective To analyze the influencing factors of recurrent hepatitis B cirrhosis. Methods 45 cases of hepatitis B patients with recurrent cirrhosis after treatment were selected as the observation group. 45 cases of the first incidence of hepatitis B cirrhosis in the same period were selected as the control group. The results of immunohistochemistry and liver histopathology Check and other factors for quantitative analysis. Results Chronic hepatitis B (CHB) history, operation history, high degree of inflammation in liver tissue, history of negative history of parents, drinking history, low cholesterol, low leukopenia, low cholinesterase, gastric varices, liver tissue immunohistochemistry HBcAg Expression and high PCR-HBVDNA quantification are the important influencing factors of recurrent hepatitis B cirrhosis. Conclusions Various factors affecting recurrent cirrhotic liver cirrhosis after hepatitis B are familiar, and familiarity with risk factors and antiviral therapy are important measures to prevent recurrent cirrhosis.