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52名HAV抗体阴性的儿童,按0、3个月免疫程序,经2针低剂量(5.50lgCCID50/ml)甲型肝炎减毒活疫苗免疫,于第2针接种后7天检测HAV抗体阳转率为100%,抗体效价GMT值为1∶14;全部接种儿童的ALT均在正常范围内(2~24μl);免前HAV抗体阳性的儿童,经2针免疫后,抗体效价增长在2倍以上
Fifty-two children with negative HAV antibody were immunized with 2-dose low-dose (5.50lg CCID50 / ml) attenuated live attenuated Hepatitis A vaccine according to a 0,3-month immunization schedule. HAV antibody positive was detected 7 days after the second needle inoculation The GMT value of the antibody titer was 1:14; the ALT of all vaccinated children was within the normal range (2 ~ 24μl); the antibody titer increased after 2 doses of immunization without pre-HAV antibody More than 2 times