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目的探讨C-反应蛋白在慢性肾衰维持性血液透析患者中的表达及临床意义。方法对患者进行透极每周2～3次,每次4h。结果血液透析患者Hb、ALB水平降低,而Scr水平显着增高,与对照组比较差异有显著性(P<0.05),血液透析可显着降低外周血Scr水平,但却可诱导CRP水平增高。结论动态监测尿毒症患者的CRP有助于及早发现患者的潜在危险因素,早期控制微炎症状态、纠正贫血、改善营养不良,对延长维持性透析患者的生存时间、提高生存率有临床指导作用。
Objective To investigate the expression and clinical significance of C-reactive protein in chronic hemodialysis patients with chronic renal failure. Methods Patients were thoroughly penetrated 2 ~ 3 times a week, each time 4h. Results The levels of Hb and ALB decreased while the levels of Scr increased significantly in hemodialysis patients compared with the control group (P <0.05). Hemodialysis can significantly reduce the level of Scr in peripheral blood but can increase the level of CRP. Conclusions The dynamic monitoring of CRP in patients with uremia can help to detect the potential risk factors of patients early, control the status of micro-inflammation early, correct anemia, improve malnutrition, and prolong the survival time and improve the survival rate of maintenance hemodialysis patients.