论文部分内容阅读
本文报道对7例不稳定的Ⅰ型糖尿病病人应用胰岛素注射笔(NOVO-PenI)代替传统的注射器进行多次胰岛素注射的强化胰岛素治疗(IIT)的结果。经1个月对照期和3个月观察,结果采用IIT治疗后,全部病人空腹/餐后血糖由对照期10.6±2.5/16.2±3.9mmol/L降至正常6.5±0.9/7.0±2.2mmol/L,HbA_1由IIT前平均10.2％降为8.2％(正常6～8％),7个时点(餐前、后1 1/2小时及夜间)血糖和游离胰岛素曲线由波动转为平稳,说明IIT能有效地控制不稳定Ⅰ型糖尿病病人的血糖。而使用胰岛素注射笔优于传统的注射器,不仅携带使用方便而且无痛。因而使得这种多次胰岛素注射方案更加可行。
This article reports the results of intensive insulin therapy (IIT) using insulin injection pen (NOVO-PenI) instead of conventional syringe for multiple insulin in seven patients with unstable type I diabetes. After 1 month of control and 3 months of observation, the results of IIT treatment, all patients fasting / postprandial blood glucose decreased from the control period 10.6 ± 2.5 / 16.2 ± 3.9mmol / L to normal 6.5 ± 0.9 / 7.0 ± 2.2mmol / L, HbA_1 was reduced from 10.2% before IIT to 8.2% (normal 6 ~ 8%). The blood glucose and free insulin curve changed from fluctuation to stable at 7 time points (before meal, after 1 1/2 hours and at night) IIT can effectively control unstable type 1 diabetes in patients with blood sugar. The use of insulin pen injection superior to traditional syringes, not only easy to carry and painless. Thus making this multiple insulin injection scheme more feasible.