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目的探讨早产合并胎膜早破(PPROM)发生的危险因素及降低围生儿病死率的恰当处理方法。方法对我院2005~2007年间早产合并胎膜早破110例孕妇进行回顾性分析。结果感染、臀位、多胎、早产流产史及妊高征占PPROM病因的前5位;孕周<34周围生儿病死率显著高于≥34周,差异有统计学意义(P<0.01)。结论提高早产合并胎膜早破的预防及诊断水平,适当延长孕龄、促胎肺成熟,尽可能延至34周以后分娩,可望降低围生儿病死率。
Objective To investigate the risk factors for premature rupture of membranes (PPROM) and the appropriate treatment to reduce perinatal mortality. Methods A retrospective analysis was performed on 110 pregnant women with premature rupture of membranes in our hospital from 2005 to 2007. Results The incidence of infection, breech, multiple births, premature labor and abortion accounted for the top five causes of PPROM. The neonatal mortality rate around 34 gestational weeks was significantly higher than that of ≥34 weeks, with statistical significance (P <0.01). Conclusions To improve the prevention and diagnosis of premature rupture of membranes with premature rupture of membranes, prolong the gestational age and promote fetal lung maturity. After prolonged delivery to 34 weeks, it is possible to reduce the perinatal mortality.