标准外伤大骨瓣开颅术治疗重型颅脑损伤患者的临床疗效

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:zmn100200
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目的探讨标准外伤大骨瓣开颅术治疗重型颅脑损伤患者的临床疗效。方法选取2013年1月至2015年6月中国医科大学附属盛京医院大连医院收治的78例重型颅脑损伤患者作为研究对象,按随机数字表法将其分为观察组(45例)和对照组(33例)。观察组患者采用标准外伤大骨瓣开颅术进行治疗,对照组患者行常规骨瓣开颅术,比较两组患者的临床疗效、术后颅内压变化情况及并发症发生情况。结果观察组患者恢复良好率明显高于对照组,病死率明显低于对照组,差异均有统计学意义(均P<0.05);术后1、3、7 d,观察组患者的颅内压均明显低于对照组,差异均有统计学意义(均P<0.05);观察组患者的脑切口疝及硬膜下积液发生率均明显低于对照组,差异均有统计学意义(均P<0.05)。结论标准外伤大骨瓣开颅术治疗重型颅脑损伤患者的临床疗效优于常规骨瓣开颅术,减压彻底,术后并发症较少。 Objective To investigate the clinical effect of craniotomy with standard trauma craniectomy on severe traumatic brain injury. Methods Seventy-eight patients with severe craniocerebral injury admitted to Shengjing Hospital of Shengjing Hospital, China Medical University from January 2013 to June 2015 were enrolled in this study. According to the random number table, they were divided into observation group (45 cases) and control group Group (33 cases). The patients in the observation group were treated by the standard craniotomy with large bone flap. The patients in the control group underwent conventional craniotomy for craniotomy. The clinical efficacy, postoperative intracranial pressure changes and complication were compared between the two groups. Results The recovery rate in the observation group was significantly higher than that in the control group, and the mortality was significantly lower than that in the control group (all P <0.05). At 1, 3 and 7 days after operation, the intracranial pressure (All P <0.05). The incidences of brain incisional hernia and subdural effusion in the observation group were significantly lower than those in the control group, both of which were statistically significant (both P <0.05). Conclusions The clinical curative effect of standard traumatic craniotomy on severe traumatic brain injury is better than that of conventional craniotomy. The decompression is complete and there are few postoperative complications.
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