异常孕产史妇女与沙眼衣原体感染关系的研究

• 作 者: 于秀丽 韩维田 于平 边超英 杨学芳 齐国艳
• 机 构: 辽宁省计划生育科学研究院优生室,辽宁省人民医院妇产科
• 出 处: 中国优生与遗传杂志
• 发表日期: 1999年02期
• 关键词: 孕产史 沙眼衣原体感染 聚合酶链反应 宫颈粘液 畸形儿 输卵管性不孕 宫内感染 宿主细胞 反应管 泌尿生殖道感染

本文用聚合酶链反应（ＰＣＲ）检测１５１例异常孕产史妇女和３２例正常孕产史妇女宫颈粘液中沙眼衣原体（ＣＴ）的感染。结果：异常孕产史妇女ＣＴ－ＰＣＲ阳性率为２５１７％，正常孕产史妇女的阳性率为６２５％，两者差异具有显著性（Ｐ＜００５）；其中流产史、死胎史、畸形儿史妇女的阳性率分别为２３１９％、３０５６％和２３９１％。结论：ＣＴ感染极可能是引起异常孕产史的主要原因之一。提出应重视妇女孕前、孕期ＣＴ感染的检测，以防止异常妊娠的出现。

In this paper, polymerase chain reaction (PCR) was used to detect the infection of C. trachomatis (CT) in 151 cases of abnormal pregnant women and 32 cases of normal pregnant women with cervical mucus. Results: The positive rate of CT-PCR in women with abnormal pregnancy was 2517%, and the positive rate of women with normal pregnancy was 625% (P <005). The history of abortion, The positive rates of history of stillbirth and malformation were 23.19%, 30.56% and 23.91% respectively. Conclusion: CT infection is most likely one of the main causes of abnormal pregnancy history. It is suggested that women should pay attention to the detection of CT infection before pregnancy and pregnancy to prevent the appearance of abnormal pregnancy.