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目的探讨骨密度减低对老年冠心病的影响。方法选取老年患者102例,根据冠心病诊断标准将其分为冠心病组和非冠心病组;所有患者均同期行双能X线的测定,根据骨密度检查结果分为低骨密度组和骨量正常组。比较不同性别低骨密度组和骨量正常组之间冠心病发病率的差异,分析低骨密度对冠心病发病率的影响。结果 1冠心病组与非冠心病组体质量指数(BMI)、吸烟、高血压、糖尿病、高血脂、低骨密度比较差异有统计学意义(P<0.05);年龄、性别、冠心病家族史、服用骨密度药物(类固醇激素及双磷酸盐类)、血清肌酐、血清钙比较差异未见统计学意义;2男性患者低骨密度组与骨量正常组间冠心病发病率比较差异未见统计学意义(P>0.05);女性患者骨密度减低组与骨量正常组间冠心病发病率比较差异有统计学意义(P<0.05);3与冠心病的危险因素比较,高血压、糖尿病、高血脂、吸烟、低骨密度的相对危险度分别为7.983、7.626、7.097、5.681、5.978。结论骨密度减低与老年冠心病存在相关性;在女性患者中更为显著;同时,相对于传统危险因素,骨密度减低导致老年冠心病的风险值得警惕。
Objective To investigate the effect of bone mineral density reduction on elderly patients with coronary heart disease. Methods A total of 102 elderly patients were selected and divided into coronary heart disease group and non-coronary heart disease group according to the diagnostic criteria of coronary heart disease. All patients underwent dual-energy X-ray examination at the same period. According to the BMD results, they were divided into low BMD group The normal group. The differences of incidence of coronary heart disease between different sex low BMD groups and normal bone mass groups were compared, and the influence of low BMD on the incidence of coronary heart disease was analyzed. Results There was significant difference in body mass index (BMI), smoking, hypertension, diabetes mellitus, hyperlipidemia and low bone density between CHD group and non-CHD group (P <0.05) , There was no statistical significance in taking bone mineral density drugs (steroid hormones and bisphosphonates), serum creatinine, and serum calcium. There was no statistical difference in the prevalence of coronary heart disease between low BMD group and normal BMD group (P> 0.05). There was significant difference in the incidence of coronary heart disease among female patients with bone mineral density reduction group and normal bone mass group (P <0.05) .3 Compared with risk factors of coronary heart disease, hypertension, diabetes mellitus, The relative risk of hyperlipemia, smoking and low BMD were 7.983, 7.626, 7.097, 5.681 and 5.978, respectively. Conclusions The decrease of bone mineral density is related to elderly coronary heart disease. It is more significant in female patients. Meanwhile, the risk of elderly patients with coronary heart disease is weaker than the traditional risk factors.