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目的:探讨卡泊芬净治疗重症卡氏肺饱子菌肺炎的临床诊断及治疗方法。方法:回顾性分析2010年1月~2014年12月期间我院收治的卡氏肺孢子菌肺炎患者80例为研究对象,对患者临床特征、实验室检查指标、胸部CT表现及临床治疗进行统计分析,为临床诊治提供依据。结果:80例并卡氏肺孢子菌肺炎患者中,咳痰、咳嗽80例;发热76例、胸闷气喘56例、呼吸衰竭21例。CD4T细胞不足50个/ul者62例、胸部CT显示玻璃样阴影64例;在治疗方法选择上,采用卡泊芬净,经治疗,76例患者病情好转,4例患者失访。结论:卡氏肺孢子菌肺炎发病率高,但是临床病原体检出率低,如判断为卡氏肺孢子菌肺炎,则可选用卡泊芬净治疗,以改善患者病情,降低患者病死率。
Objective: To investigate the clinical diagnosis and treatment of caspofungin in treating severe Pneumocystis carinii pneumonia. Methods: 80 patients with Pneumocystis carinii pneumonia admitted in our hospital from January 2010 to December 2014 were retrospectively analyzed. The clinical characteristics, laboratory indexes, chest CT findings and clinical treatment were analyzed Analysis, provide the basis for clinical diagnosis and treatment. Results: 80 cases of pneumocystis carinii pneumonia, sputum, cough 80 cases; fever in 76 cases, chest tightness and asthma in 56 cases, 21 cases of respiratory failure. Sixty-two cases of CD4 T cells less than 50 cells / ul and chest CT showed 64 cases of glass-like shadow. In the treatment option, caspofungin was used. After treatment, 76 cases improved and 4 cases were lost. Conclusion: The incidence of Pneumocystis carinii pneumonia is high, but the detection rate of clinical pathogens is low. In the case of Pneumocystis carinii pneumonia, caspofungin may be used to improve the patient’s condition and reduce the patient’s mortality.