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众所周知,惊厥是早产儿脑室内出血(IVH)的常见并发症,然而其发生率尚不清楚。因此,作者研究了IVH婴儿的急性和远期惊厥的发生率以及与出血程度的关系。作者搜集厂1992年1月～1993年10月在Schneider儿童医院住院的1～4级IVH患儿的临床资料。IVH均由超声做出诊断。IVH分为以下4级:1级为出血局限于脑室内的脉络膜丛周围。2级为脑室内出血不合并脑积水。3级为脑室内出血并发脑积水。4级为脑室内出血并发有脑实质血肿。根据惊厥发作时神经系统的功能改变,临床上将其分为阵挛型、强直型、肌阵挛型和微小型。出生后1个月之内发生的惊厥称为急性惊厥,而1个月之后发生的惊厥称为远期惊厥。 运用Fisher精确试验来测定IVH的程度与急性和远期惊厥发生率的关系,并估算出新生儿期有急性惊厥且IVH为4级的患儿发生远期惊厥的危险性。 作者分析了103例各级IVH的患儿,其中男婴58
It is well-known that convulsions are a common complication of intraventricular hemorrhage (IVH) in preterm infants, although the incidence is unknown. Therefore, the authors studied the incidence of acute and long-term seizures and the degree of bleeding in IVH infants. The authors collected data from January 1992 to October 1993 in Schneider Children’s Hospital hospitalized patients with grade 1-4 IVH. IVH diagnosis by ultrasound. IVH is divided into the following 4: 1 grade bleeding confined to the periventricular choroid plexus. Level 2 for intraventricular hemorrhage without hydrocephalus. Grade 3 for intraventricular hemorrhage complicated with hydrocephalus. Level 4 for intracerebral hemorrhage complicated by cerebral parenchymal hematoma. According to seizures during the nervous system function changes, clinically divided into clonic, ankylotic, myoclonus and micro-type. Convulsions occurring within 1 month after birth are called acute convulsions, and convulsions occurring after 1 month are called long-term convulsions. Fisher’s exact test was used to determine the association of IVH with the incidence of acute and long-term seizures and to estimate the risk of long-term seizures in infants with acute convulsions and IVH of grade 4. The authors analyzed 103 children with IVH at all levels, of which 58 were male infants