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头抱布腾（ceft止＂ten）是新的口服头抱菌素。本文介绍了可同时测定头抱布腾及其代谢物（反式异构体）的液相色谱（LC）法，用两种LC法分别评价了其药动学和人血浆与尿排泄物。稀血浆样品在蛋白沉淀前直接注入到反相柱上，稀尿样用转换柱，样品通过自动联机纯化处理。在临床有
(Ceft only) is the new oral cephalosporin.This article describes the liquid chromatography (LC) method for the simultaneous determination of clopidogrel and its metabolite (trans isomer) with Two kinds of LC methods were respectively evaluated for their pharmacokinetics and human plasma and urinary excretion.The samples of dilute plasma were directly injected into the reversed-phase column before the protein precipitation, the sample of the dilute urine was purified by automatic on-line in the clinical Have