MRI结合数字化钼靶诊断乳腺癌的临床研究(英文)

来源 :Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:mumu
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Objective:To compare the effectiveness of digital mammography and MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of the two.Methods:Sixty-seven pa- tients with surgery and pathology proved breast lesion(malignant,n=32;benign,n=46)underwent digital mammography and MRI,the pulse sequences included T_1WI,T_2WI,diffuse weighted imaging(DWI),and dynamic contrast-enhanced MRI before surgery.Of the results of these two modalities,all lesions were classified into 5 groups according to BI-RADS classifica- tion,and the imaging findings were correlated to histopathology.The sensitivity and specificity of each modality as well as the combination of the two were calculated.Results:Of these 78 breasts lesions,The sensitivity was 78.13%%(25/32)for digital mammography and 93.75%(30/32)for MRI(P>0.05).The specificity was 73.91%%(34/46)and 89.13%(41/46)accordingly (P<0.05),both of them showed statistical difference.The sensitivity and specificity was 98.63% and 97.16% respectively as these two modalities were used in combination.Conclusion:Digital mammography in combination with MRI is helpful in the diagnosis of breast cancer,the sensitivity and specificity was enhanced when compared to that of single modality. Objective: To compare the effectiveness of digital mammography and MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of the two. Methods: Sixty-seven pa- tients with surgery and pathology proved breast lesion (malignant, n = 32; benign, n = 46) underwent digital mammography and MRI, the pulse sequences included T_1WI, T_2WI, diffuse weighted imaging (DWI), and dynamic contrast- enhanced MRI before surgery. Of the results of these two modalities, all lesions were classified into 5 groups according to BI-RADS classifica- tion, and the imaging findings were correlated to histopathology. sensitivity and specificity of each modality as well as the combination of the two were calculated. Results: Of these 78 breasts lesions, the sensitivity was 78.13% (25/32) for digital mammography and 93.75% (30/32) for MRI (P> 0.05) .the specificity was 73.91% (34/46) and 89.13% (41 / 46) accordingly (P <0.05), both of them showed statistical difference. The sensitivi ty and specificity was 98.63% and 97.16% respectively as both two modals were used in combination. Confound: Digital mammography in combination with MRI is helpful in the diagnosis of breast cancer, the sensitivity and specificity was enhanced when compared to that of single modality.
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