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SLE发生严重的血小板减少性鼻衄者较为罕见,本文报道1例如下: 病例报告患者女性,33岁,工人,因反复四肢关节疼痛4年,双手指雷诺氏现象3年,发烧伴乏力1月以SLE于1989年6月15日收入我科治疗。患者于3年前因ANA阳性,SR及γ球蛋白升高伴上述临床表现疑诊为混合结缔组织病在我科住院,经强的松40mg/日及海棠合剂60ml/日治疗,病情缓解递减为强的松10mg/日维持量出院。1月前因感冒上呼吸道感染使病情复发加重,经强的松20mg/日及青霉素抗感染效差且伴高烧而再次入院。查体:T38℃,贫血貌,心肺(-),肝肋下2cm,质中,触痛,脾未及,关节无红肿畸型。皮肤科情况:
SLE severe thrombocytopenia is relatively rare in patients with epistaxis, reported in 1 case as follows: Case Report Female patients, 33 years old, workers, because of repeated limbs and joints pain for 4 years, fingers mean Raynaud’s phenomenon for 3 years, fever and fatigue in January To SLE in June 15, 1989 revenue treatment of our department. Patients with ANA-positive, SR and gamma globulin increased with the clinical manifestations of suspected three years ago mixed connective tissue disease hospitalized in our department, the prednisone 40mg / day and Begonia mixture 60ml / day treatment, the disease eased down For prednisone 10mg / day maintenance discharge. 1 month ago due to upper respiratory tract infection so that the recurrence of aggravating conditions, the prednisone 20mg / day and penicillin anti-infective poor with high fever and re-admission. Physical examination: T38 ℃, anemia appearance, cardiopulmonary (-), liver ribs 2cm, quality, tenderness, spleen, joint no swelling and malformations. Dermatology: