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血管内皮细胞功能障碍是高血压血管损伤的临床重要标志之一。因此,检测血管内皮细胞功能对于高血压的预防、诊治及预后评估具有重要的临床价值[1]。内皮微颗粒(endothelial microparticles,EMP)是细胞激活、损伤或凋亡时从内皮细胞的细胞膜脱落下来并携带来自内皮细胞某些抗原特性的微颗粒,其直径为0.2~1.0μm[2]。近年的研究表明,EMP能反映内皮细胞激活、增殖及凋亡的平衡状态,是内皮细胞功能障
Vascular endothelial dysfunction is one of the most important clinical signs of vascular injury in hypertension. Therefore, the detection of vascular endothelial cell function for the prevention, diagnosis and treatment of hypertension and prognostic evaluation of important clinical value [1]. Endothelial microparticles (EMPs) are microparticles that fall off the cell membrane of endothelial cells during cell activation, injury, or apoptosis and carry certain antigenic properties from endothelial cells and have diameters of 0.2-1.0 μm [2]. In recent years, studies have shown that EMP can reflect the balance of endothelial cell activation, proliferation and apoptosis is endothelial cell dysfunction