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目的研究左心室三维应力与反映左心室收缩功能的生物力学指标——最大心肌劲度(maxEav)的相关性,以获得反映左心室收缩功能的简单且实用的生物力学指标。方法选取34例健康人为研究对象,其中男性19例,女性15例;年龄34～75岁,平均年龄49.2岁。应用超声心动图测定心脏左心室收缩末期内径和后壁厚度及射血分数;左心室收缩末期中壁长短径、室壁厚度;联合袖带肱动脉血压值计算左心室收缩末期压力。应用上述各测值计算maxEav及左心室收缩末期径线、圆周、长轴应力(σr、σθ、σm),进行相关性统计学分析。结果σr=(-62.55±0.53)N/cm2;σθ=(27.81±1.36)N/cm2;σm=(62.58±2.88)N/cm2;maxEav=(226.52±9.36)N/cm2;LVEF=(63.13±1.01)%。maxEav与σr无相关性(r=0.067,P>0.05);maxEav与σθ有极显著负相关性(r=-0.510,P<0.01);maxEav与σm有极显著正相关性(r=0.563,P<0.01)。LVEF与三向应力无相关性(P>0.05)。结论应用左心室收缩末期圆周及长轴应力两项生物力学指标评价左心室收缩功能较为简便实用且准确。
Objective To study the correlation between left ventricular three-dimensional stress and biomechanical parameter-maxEav that reflects left ventricular systolic function in order to obtain a simple and practical biomechanical index reflecting left ventricular systolic function. Methods 34 healthy subjects were selected as study subjects, including 19 males and 15 females, aged from 34 to 75 years with a mean age of 49.2 years. The left ventricular end systolic diameter and posterior wall thickness and ejection fraction were measured by echocardiography. The medial wall short-length and wall thickness at the end of left ventricular end-systole were measured. The systolic pressure of left ventricular end-systolic pressure was calculated by the cuff brachial artery blood pressure. Applying the above measurements to calculate maxEav and left ventricular end systolic diameter, circumference, long axis stress (σr, σθ, σm), the correlation between statistical analysis. Results σr = (-62.55 ± 0.53) N / cm2; σθ = (27.81 ± 1.36) N / cm2; σm = (62.58 ± 2.88) N / cm2; maxEav = (226.52 ± 9.36) N / ± 1.01)%. There was a significant negative correlation between maxEav and σθ (r = -0.510, P <0.01). There was a significant positive correlation between maxEav and σm (r = 0.563, P <0.01). There was no correlation between LVEF and three-dimensional stress (P> 0.05). Conclusion The assessment of left ventricular systolic function using two biomechanical indexes of left ventricular end-systole circumference and long-axis stress is simple, practical and accurate.