论文部分内容阅读
众所周知,急性放射病一般分为三种类型:骨髓型、胃肠型和脑型。它们都有各自的特征,例如剂量范围,活存时间、靶器官等均各不相同。本文通过一些指标的测量,观察1～20戈瑞范围内不同剂量γ线对骨髓型和胃肠型急性放射病靶器官的效应,探讨这两型放射病指标的剂量-效应特点。材料与方法实验动物 LACA系自由繁殖小白鼠,10周龄。雄性者体重25～35克,雌性20～30克。以~(60)C_0γ线一次全身照射。照射后72小时进行各指标的测量。第一批实验雄性小鼠,剂量1～20戈瑞(剂量间隔1戈瑞),照射量率85.7—98.8伦/分。每个剂量组20只动物,另有20只不受照射的正常动物作为对照组。照射后72小时断头活杀。对每组中的10只动物取出胸腺和脾
As we all know, acute radiation sickness is generally divided into three types: bone marrow type, gastrointestinal type and brain type. They all have their own characteristics, such as dose range, survival time, target organs, etc. are different. In this paper, we observed the effects of different doses of γ-ray in the range of 1 ~ 20 Gy on the target organ of myeloid and gastrointestinal acute radiation disease and the dose-response characteristics of these two types of radiological disease indicators. MATERIALS AND METHODS Experimental animals LACA were free-breeding mice, 10 weeks old. Male weight 25 to 35 grams, 20 to 30 grams of females. A ~ (60) C_0γ line a total body irradiation. The measurement of each index was performed 72 hours after irradiation. The first experimental male mice, doses of 1 to 20 Gy (dose interval of 1 Gy), the exposure rate of 85.7-98.8 Lun / min. Twenty animals per dose group and another 20 normal animals that were not exposed were used as controls. 72 hours after irradiation decapitated live kill. Thymus and spleen were removed from 10 animals in each group