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阻塞性睡眠呼吸暂停(obstructive sleep apnoea,OSA)与高血压常常并存,两者均与夜间尿钠排泄率(urine sodium excretion rate,UNaV)较白天高相关。然而,其中的具体机制尚不清楚。研究人员比较伴或不伴有OSA的高血压患者和正常血压者UNaV的昼夜节律差异。方法:纳入高血压患者[血压>140/90mm Hg(1mm Hg=0.133kPa),或服用除利尿剂
Obstructive sleep apnea (OSA) often coexists with high blood pressure, both of which are associated with high nighttime urinary sodium excretion rate (UNaV). However, the specific mechanism is not yet clear. The researchers compared circadian rhythms of UNaV with and without hypertension in OSA-treated hypertensive patients. METHODS: Patients with hypertension (> 140/90 mm Hg (1 mm Hg = 0.133 kPa) or patients taking diuretics