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用免疫组化ＡＢＣ法，观察了４７例结肠癌肠系膜淋巴结中Ｓ－１００蛋白阳性细胞的密度与分布。结果显示：阳性细胞可分为圆型、短突起和长突起型３种。阳性细胞在癌周区高于残存区，并形成围绕癌的反应带，可见阳性细胞与癌接触。无转移组阳性细胞密度高于转移组和非癌组。提示该类细胞在抗肿瘤免疫中有一定作用。
Using immunohistochemical ABC method, the density and distribution of S-100 protein-positive cells in 47 mesenteric lymph nodes were observed. The results showed that: positive cells can be divided into round, short protrusions and long protrusions. The positive cells were higher in the pericancerous area than in the remaining area and formed a reaction band surrounding the cancer. It was found that the positive cells were in contact with the cancer. The density of positive cells in the non-metastatic group was higher than that in the metastatic group and the non-cancer group. It is suggested that this type of cells has a role in anti-tumor immunity.